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G protein-coupled Receptor 30 (GPR30) Forms a Plasma Membrane Complex with Membrane-associated Guanylate Kinases (MAGUKs) and Protein Kinase A-anchoring Protein 5 (AKAP5) That Constitutively Inhibits cAMP Production
GPR30, or G protein-coupled estrogen receptor, is a G protein-coupled receptor reported to bind 17β-estradiol (E(2)), couple to the G proteins G(s) and G(i/o), and mediate non-genomic estrogenic responses. However, controversies exist regarding the receptor pharmacological profile, effector coupling...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139225/ https://ncbi.nlm.nih.gov/pubmed/24962572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.566893 |
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