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The C-terminal Domain of the DNA Polymerase Catalytic Subunit Regulates the Primase and Polymerase Activities of the Human DNA Polymerase α-Primase Complex

The initiation of DNA synthesis during replication of the human genome is accomplished primarily by the DNA polymerase α-primase complex, which makes the RNA-DNA primers accessible to processive DNA pols. The structural information needed to understand the mechanism of regulation of this complex bio...

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Bibliografski detalji
Glavni autori: Zhang, Yinbo, Baranovskiy, Andrey G., Tahirov, Tahir H., Pavlov, Youri I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139218/
https://ncbi.nlm.nih.gov/pubmed/24962573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570333
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