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Circulating tumor cells exhibit a biologically aggressive cancer phenotype accompanied by selective resistance to chemotherapy

With prostate cancer (PCa), circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) portend a poor clinical prognosis. Their unknown biology precludes rational therapeutic design. We demonstrate that CTC and DTC cell lines, established from mice bearing human PCa orthotopic implants, exhi...

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Autors principals: Pavese, Janet M., Bergan, Raymond C.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139115/
https://ncbi.nlm.nih.gov/pubmed/25016063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.06.012
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