Llwytho...

Asteropsins B–D, sponge-derived knottins with potential utility as a novel scaffold for oral peptide drugs

BACKGROUND: Known linear knottins are unsuitable as scaffolds for oral peptide drug due to their gastrointestinal instability. Herein, a new subclass of knottin peptides from Porifera is structurally described and characterized regarding their potential for oral peptide drug development. METHODS: As...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Huayue, Bowling, John J., Su, Mingzhi, Hong, Jongki, Lee, Bong-Jin, Hamann, Mark T., Jung, Jee H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139099/
https://ncbi.nlm.nih.gov/pubmed/24225326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.11.001
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