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CLEC‐2‐dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP
BACKGROUND: The activation of platelet CLEC‐2 by podoplanin on lymphatic endothelial cells (LECs) has a critical role in prevention of mixing of lymphatic and blood vasculatures during embryonic development. Paradoxically, LECs release cAMP and cGMP‐elevating agents, prostacyclin (PGI(2)) and nitric...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Blackwell Pub
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138994/ https://ncbi.nlm.nih.gov/pubmed/24460629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12514 |
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