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Inhibitors of Sclerostin – Emerging Concepts

PURPOSE OF REVIEW: Recent data suggest that inhibitors of sclerostin, an osteocyte-produced Wnt signaling pathway antagonist, can stimulate bone formation. This review provides rationale and summarizes recent evidence supporting this novel approach to skeletal anabolism. RECENT FINDINGS: Data from n...

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Détails bibliographiques
Auteurs principaux: Drake, Matthew T., Farr, Joshua N.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138969/
https://ncbi.nlm.nih.gov/pubmed/24807403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0000000000000073
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