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Phenotype of the Anti-Rickettsia CD8(+) T cell Response suggests cellular correlates of protection for the assessment of novel antigens

The obligately intracellular bacteria Rickettsia infect endothelial cells and cause systemic febrile diseases that are potentially lethal. No vaccines are currently available and current knowledge of the effective immune response is limited. Natural and experimental rickettsial infections provide st...

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Detalhes bibliográficos
Main Authors: Caro-Gomez, Erika, Gazi, Michal, Cespedes, Maria A., Goez, Yenny, Teixeira, Bruno, Valbuena, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138832/
https://ncbi.nlm.nih.gov/pubmed/25043277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.07.032
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