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Differentially Regulated Protein Kinase A (PKA) Activity in Adipose Tissue and Liver Is Associated With Resistance to Diet-Induced Obesity and Glucose Intolerance in Mice That Lack PKA Regulatory Subunit Type IIα

The cAMP-dependent protein kinase A (PKA) signaling system is widely expressed and has a central role in regulating cellular metabolism in all organ systems affected by obesity. PKA has four regulatory (RIα, RIIα, RIβ, RIIβ) and four catalytic (Cα, Cβ, Cγ, Prkx) subunit isoforms that have tissue-spe...

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Detalhes bibliográficos
Main Authors: London, Edra, Nesterova, Maria, Sinaii, Ninet, Szarek, Eva, Chanturiya, Tatyana, Mastroyannis, Spyridon A., Gavrilova, Oksana, Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138573/
https://ncbi.nlm.nih.gov/pubmed/24914943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1122
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