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Regulation of COX-2 expression by miR-146a in lung cancer cells

Prostaglandins are a class of molecules that mediate cellular inflammatory responses and control cell growth. The oxidative conversion of arachidonic acid to prostaglandin H(2) is carried out by two isozymes of cyclooxygenase, COX-1 and COX-2. COX-1 is constitutively expressed, while COX-2 can be tr...

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Bibliographic Details
Main Authors: Cornett, Ashley L., Lutz, Carol S.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138325/
https://ncbi.nlm.nih.gov/pubmed/25047043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.044149.113
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