Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter

Interstitial concentration of amyloid beta (Aß) is positively related to synaptic activity in animal experiments. In humans, Aß deposition in Alzheimer's disease overlaps with cortical regions highly active earlier in life. White matter lesions (WML) disrupt connections between gray matter (GM)...

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Bibliografiska uppgifter
Huvudupphovsmän: Glodzik, L., Kuceyeski, A., Rusinek, H., Tsui, W., Mosconi, L., Li, Y., Osorio, R.S., Williams, S., Randall, C., Spector, N., McHugh, P., Murray, J., Pirraglia, E., Vallabhajosula, S., Raj, A., de Leon, M.J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138232/
https://ncbi.nlm.nih.gov/pubmed/24999038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2014.06.060
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