Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter

Interstitial concentration of amyloid beta (Aß) is positively related to synaptic activity in animal experiments. In humans, Aß deposition in Alzheimer's disease overlaps with cortical regions highly active earlier in life. White matter lesions (WML) disrupt connections between gray matter (GM)...

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Detalhes bibliográficos
Main Authors: Glodzik, L., Kuceyeski, A., Rusinek, H., Tsui, W., Mosconi, L., Li, Y., Osorio, R.S., Williams, S., Randall, C., Spector, N., McHugh, P., Murray, J., Pirraglia, E., Vallabhajosula, S., Raj, A., de Leon, M.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138232/
https://ncbi.nlm.nih.gov/pubmed/24999038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2014.06.060
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