The IκB Kinase Complex Is Required for Plexin-B-Mediated Activation of RhoA

Plexins are widely expressed transmembrane proteins that mediate the cellular effects of semaphorins. The molecular mechanisms of plexin-mediated signal transduction are still poorly understood. Here we show that signalling via B-family plexins leading to the activation of the small GTPase RhoA requ...

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Detaylı Bibliyografya
Asıl Yazarlar: Zielonka, Matthias, Krishnan, Ramesh K., Swiercz, Jakub M., Offermanns, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138210/
https://ncbi.nlm.nih.gov/pubmed/25137062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105661
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