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Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells()

Interleukin 6 (IL-6) and tumor necrosis factor alpha (TNFα) are proinflammatory cytokines that play a critical role in inflammatory bowel disease, as well as in colorectal tumorigenesis. We hypothesize that these cytokines modulate the expression and thus activity of the vitamin D system in colonic...

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Detalhes bibliográficos
Main Authors: Hummel, Doris M., Fetahu, Irfete S., Gröschel, Charlotte, Manhardt, Teresa, Kállay, Enikő
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138205/
https://ncbi.nlm.nih.gov/pubmed/24120915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2013.09.017
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