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Epigenetic regulation of the 1,25-dihydroxyvitamin D(3) 24-hydroxylase (CYP24A1) in colon cancer cells
Calcitriol is the hormonally active form of vitamin D and has anti-proliferative and pro-apoptotic effects. Calcitriol and its precursor calcidiol (25(OH)D(3)) are degraded by the 1,25-dihydroxyvitamin D(3) 24-hydroxylase (CYP24A1). This enzyme is overexpressed in colorectal tumors, however, the mec...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Pergamon
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695570/ https://ncbi.nlm.nih.gov/pubmed/22940288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2012.08.003 |
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