NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

BACKGROUND: Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM). We aimed to explore whether NLRP3 inflammasome activation contributes to DCM and the...

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Detalhes bibliográficos
Main Authors: Luo, Beibei, Li, Bo, Wang, Wenke, Liu, Xiangjuan, Xia, Yanfei, Zhang, Cheng, Zhang, Mingxiang, Zhang, Yun, An, Fengshuang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138036/
https://ncbi.nlm.nih.gov/pubmed/25136835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104771
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