Combination of angiotensin-(1–7) with perindopril is better than single therapy in ameliorating diabetic cardiomyopathy

We recently found that overexpression of angiotensin (Ang)-converting enzyme 2, which metabolizes Ang-II to Ang-(1–7) and Ang-I to Ang-(1–9), may improve left ventricular remodeling in diabetic cardiomyopathy. Here we aimed to test whether chronic infusion of Ang-(1–7) can dose-dependently ameliorat...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hao, Panpan, Yang, Jianmin, Liu, Yanping, Zhang, Mingxiang, Zhang, Kai, Gao, Fei, Chen, Yuguo, Zhang, Cheng, Zhang, Yun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350094/
https://ncbi.nlm.nih.gov/pubmed/25740572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08794
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