Preclinical Evaluation of the Engineered Stem Cell Chemokine Stromal Cell-Derived Factor 1–alpha Analogue in a Translational Ovine Myocardial Infarction Model

RATIONALE: Following myocardial infarction (MI) there is an inadequate blood supply to the myocardium and the surrounding borderzone becomes hypocontractile. OBJECTIVE: To develop a clinically translatable therapy, we hypothesized that in a preclinical ovine model of MI, the modified endothelial pro...

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Auteurs principaux: MacArthur, John W., Cohen, Jeffrey E., McGarvey, Jeremy R., Shudo, Yasuhiro, Patel, Jay B., Trubelja, Alen, Fairman, Alexander S., Edwards, Bryan B., Hung, George, Hiesinger, William, Goldstone, Andrew B., Atluri, Pavan, Wilensky, Robert L., Pilla, James J., Gorman, Joseph H., Gorman, Robert C., Woo, Y. Joseph
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137973/
https://ncbi.nlm.nih.gov/pubmed/24366171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.302884
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