The Hypofunctional Effect of P335L Single Nucleotide Polymorphism on SSTR5 Function

INTRODUCTION: Somatostatin receptor subtype 5 (SSTR5) mediates the inhibitory effect of somatostatin on insulin expression/secretion and cell proliferation. A number of single nucleotide polymorphisms (SNPs) of SSTR5 have been identified, including P335L, a non-synonymous SNP located in the protein...

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Main Authors: Zhou, Guisheng, Gingras, Marie-Claude, Liu, Shi-He, Li, Donghui, Li, Zhijun, Catania, Robbi L., Stehling, Kelly M., Li, Min, Paganelli, Giovanni, Gibbs, Richard A, DeMayo, Franco, Fisher, William E., Brunicardi, F. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137969/
https://ncbi.nlm.nih.gov/pubmed/21249361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00268-010-0939-9
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