Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.

We have characterized the molecular nature of mutations in wingless (wg), a segment polarity gene acting during various stages of Drosophila development. Embryo-lethal alleles have undergone mutations in the protein-encoding domain of the gene, including deletions and point mutations of conserved re...

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Bibliographic Details
Main Authors: van den Heuvel, M, Harryman-Samos, C, Klingensmith, J, Perrimon, N, Nusse, R
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC413795/
https://ncbi.nlm.nih.gov/pubmed/8262072
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