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Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.

We have characterized the molecular nature of mutations in wingless (wg), a segment polarity gene acting during various stages of Drosophila development. Embryo-lethal alleles have undergone mutations in the protein-encoding domain of the gene, including deletions and point mutations of conserved re...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: van den Heuvel, M, Harryman-Samos, C, Klingensmith, J, Perrimon, N, Nusse, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06225.x
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