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Neurosteroids as endogenous regulators of seizure susceptibility and use in the treatment of epilepsy
Neurosteroids such as allopregnanolone are positive allosteric modulators of GABA(A) receptors with powerful antiseizure activity in diverse animal models. Neurosteroids may be endogenous regulators of seizure susceptibility, for example, in catamenial epilepsy. Clinical trials with the synthetic ne...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137784/ https://ncbi.nlm.nih.gov/pubmed/25147407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02870.x |
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