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Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy

This review highlights the role of major endogenous neurosteroids in seizure disorders and the promise of neurosteroid replacement therapy in epilepsy. Neurosteroids are endogenous modulators of seizure susceptibility. Neurosteroids such as allopregnanolone (3α-hydroxy-5α-pregnane-20-one) and allote...

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Bibliografski detalji
Glavni autor: Reddy, Doodipala Samba
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356070/
https://ncbi.nlm.nih.gov/pubmed/22654805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00038
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