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Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy

This review highlights the role of major endogenous neurosteroids in seizure disorders and the promise of neurosteroid replacement therapy in epilepsy. Neurosteroids are endogenous modulators of seizure susceptibility. Neurosteroids such as allopregnanolone (3α-hydroxy-5α-pregnane-20-one) and allote...

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Detalhes bibliográficos
Autor principal: Reddy, Doodipala Samba
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356070/
https://ncbi.nlm.nih.gov/pubmed/22654805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00038
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