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Deficiency in Perlecan/HSPG2 during Bone Development Enhances Osteogenesis and Decreases Quality of Adult Bone in Mice
Perlecan/Hspg2 (Pln) is a large heparan sulfate proteoglycan abundant in the extracellular matrix of cartilage and the lacuno-canalicular space of adult bones. While Pln function during cartilage development is critical, evidenced by deficiency disorders including Schwartz-Jampel Syndrome and dysseg...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137566/ https://ncbi.nlm.nih.gov/pubmed/24798737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-014-9859-2 |
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