Deficiency in Perlecan/HSPG2 during Bone Development Enhances Osteogenesis and Decreases Quality of Adult Bone in Mice

Perlecan/Hspg2 (Pln) is a large heparan sulfate proteoglycan abundant in the extracellular matrix of cartilage and the lacuno-canalicular space of adult bones. While Pln function during cartilage development is critical, evidenced by deficiency disorders including Schwartz-Jampel Syndrome and dysseg...

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Detaylı Bibliyografya
Asıl Yazarlar: Lowe, Dylan A., Lepori-Bui, Nadia, Fomin, Peter V., Sloofman, Laura G., Zhou, Xiaozhou, Farach-Carson, Mary C., Wang, Liyun, Kirn-Safran, Catherine B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137566/
https://ncbi.nlm.nih.gov/pubmed/24798737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-014-9859-2
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