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Finasteride Treatment Alters Tissue Specific Androgen Receptor Expression in Prostate Tissues

BACKGROUND: Normal and pathologic growth of the prostate is dependent on the synthesis of dihydrotestosterone (DHT) from testosterone by 5α-reductase. Finasteride is a selective inhibitor of 5α-reductase 2, one isozyme of 5α-reductase found in abundance in the human prostate. The objective of this s...

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Autores principales: Bauman, Tyler M., Sehgal, Priyanka D., Johnson, Karen A., Pier, Thomas, Bruskewitz, Reginald C., Ricke, William A., Huang, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137476/
https://ncbi.nlm.nih.gov/pubmed/24789081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22810
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