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Feasibility of administering oblimersen (G3139; Genasense) with imatinib mesylate in patients with imatinib resistant chronic myeloid leukemia – Cancer and leukemia group B study 10107

The CALGB studied the feasibility and effectiveness of adding oblimersen (G3139; Genasense) to imatinib mesylate (IM) in imatinib-resistant chronic phase chronic myeloid leukemia (CML) patients. We hypothesised that IM resistant CML cells are no longer being driven to proliferate by Bcr/Abl activity...

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Bibliographische Detailangaben
Hauptverfasser: WETZLER, MEIR, DONOHUE, KATHLEEN A., ODENIKE, OLATOYOSI M., FELDMAN, ERIC J., HURD, DAVID D., STONE, RICHARD M., WESTERFELT, PETER, BLOOMFIELD, CLARA D., LARSON, RICHARD A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137465/
https://ncbi.nlm.nih.gov/pubmed/18452072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190802043887
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