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VMAT2 and dopamine neuron loss in a primate model of Parkinson’s disease

We used positron emission tomography (PET) to measure the earliest change in dopaminergic synapses and glial cell markers in a chronic, low-dose MPTP non-human primate model of Parkinson’s disease (PD). In vivo levels of dopamine transporters (DAT), vesicular monoamine transporter-type 2 (VMAT2), am...

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Detalhes bibliográficos
Main Authors: Chen, Ming-Kai, Kuwabara, Hiroto, Zhou, Yun, Adams, Robert J., Brašić, James R., McGlothan, Jennifer L., Verina, Tatyana, Burton, Neal C., Alexander, Mohab, Kumar, Anil, Wong, Dean F., Guilarte, Tomás R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137401/
https://ncbi.nlm.nih.gov/pubmed/17988241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.05108.x
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