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Synthesis and Pharmacology of a Novel κ Opioid Receptor (KOR) Agonist with a 1,3,5-Trioxazatriquinane Skeleton
[Image: see text] We designed and synthesized the 1,3,5-trioxazatriquinane derivatives with m-hydroxyphenyl groups. These compounds include the phenethylamine structure within them, which is a common structure observed in morphinan derivatives like morphine. Among the synthesized compounds, (−)-8c w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137376/ https://ncbi.nlm.nih.gov/pubmed/25147605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000542 |
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