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Raf-1 is required for T cell IL2 production.

Engagement of the T cell receptor/CD3 complex activates the serine/threonine kinase, Raf-1, but the physiologic consequences of its activation have not been determined. The effects of Raf-1 on interleukin 2 (IL2) production in T cells were examined using activated and inhibitory forms of Raf-1. A tr...

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Autors principals: Owaki, H, Varma, R, Gillis, B, Bruder, J T, Rapp, U R, Davis, L S, Geppert, T D
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC413733/
https://ncbi.nlm.nih.gov/pubmed/8223446
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