TCR beta and TCR alpha gene enhancers confer tissue- and stage-specificity on V(D)J recombination events.

We describe transgenic mice carrying germline variable gene segments associated with either the T cell receptor (TCR) beta or alpha gene enhancers (E beta or E alpha). Transgenic constructs underwent high rates of site-specific rearrangements predominantly in T cells from independent mice. Rearrange...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Capone, M, Watrin, F, Fernex, C, Horvat, B, Krippl, B, Wu, L, Scollay, R, Ferrier, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8223443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06118.x
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