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Detecting an Overall Survival Benefit that Is Derived From Progression-Free Survival
BACKGROUND: Whether progression-free survival (PFS) or overall survival (OS) is the more appropriate endpoint in clinical trials of metastatic cancer is controversial. In some disease and treatment settings, an improvement in PFS does not result in an improved OS. METHODS: We partitioned OS into two...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137232/ https://ncbi.nlm.nih.gov/pubmed/19903805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp369 |
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