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Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide

Exposing mice to a chronic hypoxic treatment (10% oxygen, 21 days) that promotes pulmonary hypertension was observed to attenuate the pulmonary vasoconstriction response to acute hypoxia (HPV) both in vivo and in isolated pulmonary arteries. Since catalase restored the HPV response in isolated arter...

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Detalhes bibliográficos
Main Authors: Patel, Dhara, Alhawaj, Raed, Wolin, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137156/
https://ncbi.nlm.nih.gov/pubmed/24920729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00257.2013
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