Extracellular Superoxide Dismutase Overexpression Can Reverse the Course of Hypoxia-Induced Pulmonary Hypertension

Hypoxia leads to free radical production, which has a pivotal role in the pathophysiology of pulmonary hypertension (PH). We hypothesized that treatment with extracellular superoxide dismutase (EC-SOD) could ameliorate the development of PH induced by hypoxia. In vitro studies using pulmonary microv...

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Main Authors: Ahmed, Mohamed N, Zhang, Yinzhong, Codipilly, Champa, Zaghloul, Nahla, Patel, Dhara, Wolin, Michael, Miller, Edmund J
Formato: Artigo
Idioma:Inglês
Publicado: ScholarOne 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269642/
https://ncbi.nlm.nih.gov/pubmed/22045221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00339
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