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Chronic rapamycin treatment causes diabetes in male mice

Current evidence indicates that the mammalian target of rapamycin inhibitor rapamycin both increases longevity and, seemingly contradictorily, impairs glucose homeostasis. Most studies exploring the dimensions of this paradox have been based on rapamycin treatment in mice for up to 20 wk. We sought...

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Detalles Bibliográficos
Main Authors: Schindler, Christine E., Partap, Uttara, Patchen, Bonnie K., Swoap, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137151/
https://ncbi.nlm.nih.gov/pubmed/24965794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00123.2014
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