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Transdifferentiation of chicken embryonic cells into muscle cells by the 3' untranslated region of muscle tropomyosin.

Transfection with a plasmid encoding the 3' untranslated region (3' UTR) of skeletal muscle tropomyosin induces chicken embryonic fibroblasts to express skeletal tropomyosin. Such cells become spindle shaped, fuse, and express titin, a marker of striated muscle differentiation. Skeletal muscle tropo...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: L'Ecuyer, T J, Tompach, P C, Morris, E, Fulton, A B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7520
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