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New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells
DNA methylation is a well-studied epigenetic modification essential for efficient cellular differentiation. Aberrant DNA methylation patterns are a characteristic feature of cancer including myeloid malignancies such as acute myeloid leukemia (AML). Recurrent mutations in DNA modifying enzymes were...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137036/ https://ncbi.nlm.nih.gov/pubmed/24993071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.04.008 |
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