Optical mapping discerns genome wide DNA methylation profiles

BACKGROUND: Methylation of CpG dinucleotides is a fundamental mechanism of epigenetic regulation in eukaryotic genomes. Development of methods for rapid genome wide methylation profiling will greatly facilitate both hypothesis and discovery driven research in the field of epigenetics. In this regard...

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Detalhes bibliográficos
Main Authors: Ananiev, Gene E, Goldstein, Steve, Runnheim, Rod, Forrest, Dan K, Zhou, Shiguo, Potamousis, Konstantinos, Churas, Chris P, Bergendahl, Veit, Thomson, James A, Schwartz, David C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516518/
https://ncbi.nlm.nih.gov/pubmed/18667073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-68
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