Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas

BACKGROUND: Inactivation of the NF2 gene predisposes to neurofibromatosis type II and the development of schwannomas. In vitro studies have shown that loss of NF2 leads to the induction of mitogenic signaling mediated by receptor tyrosine kinases (RTKs), MAP kinase, AKT, or Hippo pathways. The goal...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Boin, Alizée, Couvelard, Anne, Couderc, Christophe, Brito, Isabel, Filipescu, Dan, Kalamarides, Michel, Bedossa, Pierre, De Koning, Leanne, Danelsky, Carine, Dubois, Thierry, Hupé, Philippe, Louvard,, Daniel, Lallemand, Dominique
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136892/
https://ncbi.nlm.nih.gov/pubmed/24558021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou020
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares