A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori–Induced Metaplasia in the Stomach

Carriage of Helicobacter pylori strains producing more active (s1/i1) forms of VacA is strongly associated with gastric adenocarcinoma. To our knowledge, we are the first to determine effects of different polymorphic forms of VacA on inflammation and metaplasia in the mouse stomach. Bacteria produci...

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Detalhes bibliográficos
Main Authors: Winter, Jody A., Letley, Darren P., Cook, Katherine W., Rhead, Joanne L., Zaitoun, Abed A. M., Ingram, Richard J. M., Amilon, Karin R., Croxall, Nicola J., Kaye, Phillip V., Robinson, Karen, Atherton, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136800/
https://ncbi.nlm.nih.gov/pubmed/24625807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu154
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