A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori–Induced Metaplasia in the Stomach

Carriage of Helicobacter pylori strains producing more active (s1/i1) forms of VacA is strongly associated with gastric adenocarcinoma. To our knowledge, we are the first to determine effects of different polymorphic forms of VacA on inflammation and metaplasia in the mouse stomach. Bacteria produci...

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Autori principali: Winter, Jody A., Letley, Darren P., Cook, Katherine W., Rhead, Joanne L., Zaitoun, Abed A. M., Ingram, Richard J. M., Amilon, Karin R., Croxall, Nicola J., Kaye, Phillip V., Robinson, Karen, Atherton, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136800/
https://ncbi.nlm.nih.gov/pubmed/24625807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu154
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