Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling

BACKGROUND: Initiation, amplitude, duration and termination of transforming growth factor β (TGFβ) signaling via Smad proteins is regulated by post-translational modifications, including phosphorylation, ubiquitination and acetylation. We previously reported that ADP-ribosylation of Smads by poly(AD...

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Main Authors: Dahl, Markus, Maturi, Varun, Lönn, Peter, Papoutsoglou, Panagiotis, Zieba, Agata, Vanlandewijck, Michael, van der Heide, Lars P., Watanabe, Yukihide, Söderberg, Ola, Hottiger, Michael O., Heldin, Carl-Henrik, Moustakas, Aristidis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136792/
https://ncbi.nlm.nih.gov/pubmed/25133494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103651
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