The Ca(2+) Sensor Protein Swiprosin-1/EFhd2 Is Present in Neurites and Involved in Kinesin-Mediated Transport in Neurons

Swiprosin-1/EFhd2 (EFhd2) is a cytoskeletal Ca(2+) sensor protein strongly expressed in the brain. It has been shown to interact with mutant tau, which can promote neurodegeneration, but nothing is known about the physiological function of EFhd2 in the nervous system. To elucidate this question, we...

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Main Authors: Purohit, Pavitra, Perez-Branguli, Francesc, Prots, Iryna, Borger, Eva, Gunn-Moore, Frank, Welzel, Oliver, Loy, Kristina, Wenzel, Eva Maria, Grömer, Teja W., Brachs, Sebastian, Holzer, Max, Buslei, Rolf, Fritsch, Kristin, Regensburger, Martin, Böhm, Konrad J., Winner, Beate, Mielenz, Dirk
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136728/
https://ncbi.nlm.nih.gov/pubmed/25133820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103976
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