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Synthetic, Non-saccharide, Glycosaminoglycan Mimetics Selectively Target Colon Cancer Stem Cells

[Image: see text] Selective targeting of cancer stem-like cells (CSCs) is a paradigm-shifting approach. We hypothesized that CSCs can be targeted by interfering with functions of sulfated glycosaminoglycans, which play key roles in cancer cell growth, invasion and metastasis. We developed a tandem,...

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Detalhes bibliográficos
Main Authors: Patel, Nirmita J., Karuturi, Rajesh, Al-Horani, Rami A., Baranwal, Somesh, Patel, Jagrut, Desai, Umesh R., Patel, Bhaumik B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136679/
https://ncbi.nlm.nih.gov/pubmed/24968014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500402f
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