Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals.

A method which allows direct cloning of intracellular substrates for receptor tyrosine kinases (RTKs) was developed. By applying this technique to the study of the epidermal growth factor receptor (EGFR) signaling pathway, we have isolated a cDNA, designated eps8, which predicts a approximately 92 k...

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Autors principals: Fazioli, F, Minichiello, L, Matoska, V, Castagnino, P, Miki, T, Wong, W T, Di Fiore, P P
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC413663/
https://ncbi.nlm.nih.gov/pubmed/8404850
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