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Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals.

A method which allows direct cloning of intracellular substrates for receptor tyrosine kinases (RTKs) was developed. By applying this technique to the study of the epidermal growth factor receptor (EGFR) signaling pathway, we have isolated a cDNA, designated eps8, which predicts a approximately 92 k...

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Bibliografiske detaljer
Main Authors: Fazioli, F, Minichiello, L, Matoska, V, Castagnino, P, Miki, T, Wong, W T, Di Fiore, P P
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC413663/
https://ncbi.nlm.nih.gov/pubmed/8404850
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