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eps15, a novel tyrosine kinase substrate, exhibits transforming activity.

An expression cloning method which allows direct isolation of cDNAs encoding substrates for tyrosine kinases was applied to the study of the epidermal growth factor (EGF) receptor (EGFR) signaling pathway. A previously undescribed cDNA was isolated and designated eps15. The structural features of th...

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Autors principals: Fazioli, F, Minichiello, L, Matoskova, B, Wong, W T, Di Fiore, P P
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC360326/
https://ncbi.nlm.nih.gov/pubmed/7689153
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