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EGF receptor uses SOS1 to drive constitutive activation of NFκB in cancer cells
Activation of nuclear factor κB (NFκB) is a central event in the responses of normal cells to inflammatory signals, and the abnormal constitutive activation of NFκB is important for the survival of most cancer cells. In nonmalignant human cells, EGF stimulates robust activation of NFκB. The kinase a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136585/ https://ncbi.nlm.nih.gov/pubmed/25071181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412390111 |
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