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NF-κB activity is constitutively elevated in c-Abl null fibroblasts

The c-abl proto-oncogene encodes a nonreceptor tyrosine kinase involved in many cellular processes, including signaling from growth factor and antigen receptors, remodeling the cytoskeleton, and responding to DNA damage and oxidative stress. Many downstream pathways are affected by c-Abl. Elevated c...

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Bibliographic Details
Main Authors: Liberatore, Rachel A., Goff, Stephen P., Nunes, Irene
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754925/
https://ncbi.nlm.nih.gov/pubmed/19805123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905935106
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