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Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation
Adaptor proteins mediate signal transduction from cell surface receptors to downstream signaling pathways. The Grb7 protein family of adaptor proteins is constituted by Grb7, Grb10, and Grb14. This protein family has been shown to be overexpressed in certain cancers and cancer cell lines. Grb7-media...
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主要な著者: | , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136552/ https://ncbi.nlm.nih.gov/pubmed/20665473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.1062 |
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