Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation

Adaptor proteins mediate signal transduction from cell surface receptors to downstream signaling pathways. The Grb7 protein family of adaptor proteins is constituted by Grb7, Grb10, and Grb14. This protein family has been shown to be overexpressed in certain cancers and cancer cell lines. Grb7-media...

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Autori principali: Siamakpour-Reihani, Sharareh, Peterson, Tabitha A., Bradford, Andrew M., Argiros, Haroula J., Haas, Laura Lowell, Lor, Siamee N., Haulsee, Zachary M., Spuches, Anne M., Johnson, Dennis L., Rohrschneider, Larry R., Shuster, Charles Brad, Lyons, Barbara A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136552/
https://ncbi.nlm.nih.gov/pubmed/20665473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.1062
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