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Central and Peripheral Administration of Antisense Oligonucleotide Targeting Amyloid Precursor Protein Improves Learning and Memory and Reduces Neuroinflammatory Cytokines in Tg2576 (APPswe) Mice

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. The World Health Organization estimates that there are currently 18 million people worldwide living with AD and that number is expected to double by early 2025. Currently, there are no therapies to stop or reverse the symptoms of A...

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Detalhes bibliográficos
Main Authors: Farr, Susan A., Erickson, Michelle A., Niehoff, Michael L., Banks, William A., Morley, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136536/
https://ncbi.nlm.nih.gov/pubmed/24577464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-131883
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